Rheumatoid arthritis (RA) is characterized by persistent inflammation of the synovial joint membrane. Over time, bone erosion, destruction of articular cartilage, and complete loss of joint integrity may occur. Finally, multiple organ systems can be affected.
RA is the most common inflammatory arthritis affecting 0.8% of the adult population worldwide. The onset usually occurs between 30 and 50 years. The AR is responsible for large health expenditures with a great economic impact due to the high level of functional deterioration. Without treatment, within 3 years of the diagnosis Keto Viante, 20 to 30% of people with RA reach permanent disability.
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